SILVER NANO-PARTICULATE COATING ON IMPLANTABLE TITANIUM DEVICES: CAN WE TEACH AN OLD DOG A NEW TRICK? —A SYSTEMATIC REVIEW

Authors

  • Ayousha Iqbal Department of Dental Materials, HBS Dental College, Islamabad, Pakistan https://orcid.org/0000-0002-6562-6130
  • Zaineb Abbas Department of Oral Biology, Bakhtawar Amin Medical and Dental College, Multan, Pakistan
  • Shamima Abdullah Department of Community Dentistry, Bakhtawer Amin medical and dental college Multan, Pakistan
  • Tatheer Fatima, Sayyeda Department of Dental Materials, HBS Dental College, Islamabad, Pakistan
  • Fizza Batool Department Of Orthodontics, Islamabad Medical and Dental College, Islamabad, Pakistan
  • Tahira Saleem Department of Physiology, HBS Medical College, Islamabad, Pakistan

Keywords:

Ag, titanium, nanoparticle, implant, implantable device, dental implant, MTT assay

Abstract

Implant materials are one of the most investigated topics in modern medicine. This review is focused only on addressing silver as coating substance on top of titanium based implantable devices, and focused on the last five years of silver coated titanium implants on human cell population. This study was conducted on Medline, PubMed, Science Direct, Scopus and Google Scholar. A time window of the previous five years was selected up to May of 2021. The study was done at HBS Dental College, Islamabad and the Higher Education Commission Library, Islamabad. The multi-location reviewing and gathering of articles assured lack of bias in the article selection. The search for articles was done using prescribed keywords and then the sieving of articles further using systemic review methodology via PRISMA flowchart. There was excessive evidence to suggest that the surface modification with silver is effective to eliminate surface microbes which might interfere in good quality healing of bone around the titanium implant material. Silver has great antimicrobial activity however it does not show simultaneously just as good compatibility. This study points towards evidence of establishing the ‘sweet spot’ between the most favourable cytotoxic concentrations and most effective antimicrobial concentrations.

Pak J Pysiol 2023;19(3):51–5

Downloads

Download data is not yet available.

References

Kazemzadeh-Narbat M, Kindrachuk J, Duan K, Jenssen H, Hancock REW, Wang R. Antimicrobial peptides on calcium phosphate-coated titanium for the prevention of implant-associated infections. Biomaterials 2010;31(36):9519–26.

Fredj N, Burleigh TD. Transpassive dissolution of copper and rapid formation of brilliant colored copper oxide films. J Electrochem Soc 2011;158(4):C104.

Namba S, Hishiki Y. Color sensitization of zinc oxide with cyanine dyes1. J Phys Chem 1965;69(3):774–9.

Kim MI, Park KS, Park HG. Ultrafast colorimetric detection of nucleic acids based on the inhibition of the oxidase activity of cerium oxide nanoparticles. Chem Commun (Camb) 2014;50(67):9577–80.

Pasquet J, Chevalier Y, Couval E, Bouvier D, Noizet G, Morlière C, et al. Antimicrobial activity of zinc oxide particles on five micro-organisms of the Challenge Tests related to their physicochemical properties. Int J Pharm 2014;460(1–2):92–100.

Sim W, Barnard RT, Blaskovich MAT, Ziora ZM. Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007–2017). Antibiotics (Basil) 2018;7(4):93.

El-Sayed SM, Amer MA, Meaz TM, Deghiedy NM, El-Shershaby HA. Microstructure optimization of metal oxide nanoparticles and its antimicrobial activity. Measurement 2020;151:107191.

Sengul AB, Asmatulu E. Toxicity of metal and metal oxide nanoparticles: a review. Environ Chem Lett 202018(5):1659–83.

Sokolov AV, Limareva LV, Iliasov PV, Gribkova OV, Sustretov AS. Methods of encapsulation of biomacromolecules and living cells. Prospects of using metal-organic frameworks. Russ J Org Chem 2021;57(4):491–505.

Radtke A, Grodzicka M, Ehlert M, J?drzejewski T, Wypij M, Goli?ska P. “To be microbiocidal and not to be cytotoxic at the same time...”–silver nanoparticles and their main role on the surface of titanium alloy implants, J Clin Med 2019;8(3):334.

Zhang H, Hatoko M, Yin D, Yang Y, Zeng Y, Komasa S, et al. Antibacterial activity and biocompatibility of nanoporous titanium doped with silver nanoparticles and coated with N-acetyl cysteine. J Hard Tissue Biol 2018;27(4):351–8.

Yang Y, Zhang Y, Hu, R, Huang Q, Wu K, Zhang L, et al. Antibacterial and cytocompatible AgNPs constructed with the assistance of Mefp-1 for orthopaedic implants, RSC Adv 2017;7(61):38434–43.

Kranz S, Guellmar A, Voelpel A, Lesser T, Tonndorf-Martini S, Schmidt J, et al. Bactericidal and biocompatible properties of plasma chemical oxidized titanium (TiOB®) with antimicrobial surface functionalization. Materials 2019;12(6):866.

Marques I da SV, Alfaro MF, Saito MT, da Cruz NC, Takoudis C, Landers R, et al. Biomimetic coatings enhance tribocorrosion behavior and cell responses of commercially pure titanium surfaces. Biointerphases 2016;11(3):031008.

Kaczmarek M, Jurczyk K, Koper JK, Paszel-Jaworska A, Romaniuk A, Lipi?ska N, et al. In vitro biocompatibility of anodized titanium with deposited silver nanodendrites, J Mater Sci 2016;51(11):5259–70.

Guan M, Chen Y, Wei Y, Song H, Gao C, Cheng H, et al. Long-lasting bactericidal activity through selective physical puncture and controlled ions release of polydopamine and silver nanoparticles-loaded TiO2 nanorods in vitro and in vivo. Int J Nanomedicine 2019;14:2903–14.

Shivaram A, Bose S, Bandyopadhyay A. Mechanical degradation of TiO2 nanotubes with and without nanoparticulate silver coating, J Mech Behav Biomed Mater 2016;59(1):508–18.

Zeng X, Xiong S, Zhuo S, Liu C, Miao J, Liu D, et al. Nanosilver/poly (DL-lactic-co-glycolic acid) on titanium implant surfaces for the enhancement of antibacterial properties and osteoinductivity, Int J Nanomedicine 2019;14:1849–63.

Zhang W, Wang S, Ge S, Chen J, Ji P. The relationship between substrate morphology and biological performances of nano-silver-loaded dopamine coatings on titanium surfaces, R Soc Open Sci 2018;5(4):172310.

Ulfah IM, Gibran K, Bachtiar BM, Ibadurrohman M, Slamet. Modification of Ti–6Al–4V alloys for dental implant and its capacity to grow human osteoblast ATCC. Biomed Eng Appl Basis Commun 2019;31(6):1950047.

Torres-Avila IP, Padilla-Martínez II, Pérez-Hernández N, Bañuelos-Hernández AE, Velázquez JC, Castrejón-Flores JL, et al. Surface modification of the Ti-6Al-4V alloy by anodic oxidation and its effect on osteoarticular cell proliferation. Coatings 2020;10(5):491.

Sun X, Gong H, Li D, Dong L, Zhao M, Wan R, Gu H. Ag+ implantation induces mechanical properties, cell adhesion and antibacterial effects of TiN/Ag multilayers in vitro. Nanomedicine 2017;12(18):2257–68.

Jamkhande A, Kakade S, Gundawar AP. Probiotics and oral health: A review. South-Asian J Cranio-Maxillofac Dent Surg 2021;1(1):14–20.

Chen J, Hu G, Li T, Chen Y, Gao M, Li Q, et al. Fusion peptide engineered “statically-versatile” titanium implant simultaneously enhancing anti-infection, vascularization and osseointegration. Biomaterials 2021;264:120446.

Zhuang Y, Ren L, Zhang S, Wei X, Yang K, Dai K. Antibacterial effect of a copper-containing titanium alloy against implant-associated infection induced by methicillin-resistant Staphylococcus aureus. Acta Biomater 2021;119:472–84.

Sreenivasagan S, Subramanian AK, Rengalakshmi S. Prevalence and Cause of Mini-Implant Failure Encountered by Orthodontic Residents. J Long Term Eff Med Implants 2021;31(4):1–4.

Halpern LR, Adams DR. Medically Complex Dental Implant Patients: Controversies About Systemic Disease and Dental Implant Success/Survival. Dent Clin North Am 2021;65(1):1–19.

Akiyama H, Yamasaki O, Kanzaki H, Tada J, Arata J. Effects of sucrose and silver on Staphylococcus aureus biofilms. J Antimicrob Chemother 1998;42(5):629–34.

Zhang S, Du C, Wang Z, Han X, Zhang K, Liu L. Reduced cytotoxicity of silver ions to mammalian cells at high concentration due to the formation of silver chloride. Toxicol In Vitro 2013;27(2):739–44.

Li L, Bi Z, Hu Y, Sun L, Song Y, Chen S, et al. Silver nanoparticles and silver ions cause inflammatory response through induction of cell necrosis and the release of mitochondria in vivo and in vitro. Cell Biol Toxicol 2021;37(2):177–91.

Vidyadharan DM, Meethal BN, Jyothilakshmi VP, Swaminathan S. Highly transparent titania in mixed organic solvent with controlled surface area and porosity. Solar Energ 2021;213:43–52.

Ueda M, Yokota T, Honda M, Lim PN, Osaka N, Makita M, et al. Regulating size of silver nanoparticles on calcium carbonate via ultrasonic spray for effective antibacterial efficacy and sustained release. Mater Sci Eng C Mater Biol Appl 2021;125:112083.

Botelho CM, Fernandes MM, Souza JM, Dias N, Sousa AM, Teixeira JA, et al. New textile for personal protective equipment—plasma chitosan/silver nanoparticles nylon fabric. Fibers 2021;9(1):3.

Lin Y, Zhang L, Yang Y, Yang M, Hong Q, Chang K, et al. Loading gentamicin and Zn2+ on TiO2 nanotubes to improve anticoagulation, endothelial cell growth, and antibacterial activities. Stem Cells Int 2021;2021:9993247.

Schuster AJ, de Abreu JLB, Pola NM, Witek L, Coelho PG, Faot F. Histomorphometric analysis of implant osseointegration using hydrophilic implants in diabetic rats. Clin Oral Investig 2021;25(10):5867–78.

Alipal J, Mohd Pu’ad NAS, Nayan NHM, Sahari N, Abdullah HZ, Idris MI, et al. An updated review on surface functionalisation of titanium and its alloys for implants applications. Mater Today Proc 2021;42:270–82.

Ständert V, Borcherding K, Bormann N, Schmidmaier G, Grunwald I, Wildemann B. Antibiotic-loaded amphora-shaped pores on a titanium implant surface enhance osteointegration and prevent infections. Bioact Mater 2021;6(8):2331–45.

Ghimire A, Song J. Anti-periprosthetic infection strategies: from implant surface topographical engineering to smart drug-releasing coatings. ACS Appl Mater Interfaces 2021;13(18)20921–37.

Downloads

Published

30-09-2023

How to Cite

1.
Iqbal A, Abbas Z, Abdullah S, Fatima T, Batool F, Saleem T. SILVER NANO-PARTICULATE COATING ON IMPLANTABLE TITANIUM DEVICES: CAN WE TEACH AN OLD DOG A NEW TRICK? —A SYSTEMATIC REVIEW. Pak J Phsyiol [Internet]. 2023 Sep. 30 [cited 2024 May 17];19(3):51-5. Available from: https://www.pjp.pps.org.pk/index.php/PJP/article/view/1464