MEDICAL IMPORTANCE OF HUMAN MICROBIOTA
DOI:
https://doi.org/10.69656/pjp.v22i1.1945Abstract
Microorganisms are always considered as pathogens but it is now estimated that less than 1% of known microbial species are pathogenic to humans. The most microbes either coexist ‘peacefully’ with humans and they are good microbes. Human microbiota inhabits the body, living on the skin, in the mouth, gut, nose, and genital tract. Although the importance of gut microbiota for digestion of foodstuffs is widely recognized, additional roles for the body’s microbes in nutrition, immunity, and other functions is being recognized now. Human microbiota regulates brain, liver, and lung health via bidirectional pathways like the microbiota-gut-brain axis, influencing mood, cognitive function, and systemic inflammation. Modern medicine is increasingly targeting the microbiome to treat diseases by using probiotics, and prebiotics to restore balance, and by using faecal microbiota transplantation.
Pak J Physiol 2026;22(1):1–2, DOI: https://doi.org/10.69656/pjp.v22i1.1945
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